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WebTEADs interacted with RUNX2 to repress RUNX2 transcriptional activity. Furthermore, VGLL4 relieved the transcriptional inhibition of TEADs by directly competing with RUNX2 to bind TEADs through its two TDU domains. Collectively, our studies demonstrate that VGLL4 plays an important role in regulating osteoblast differentiation and bone ... WebTeads for Publishers Suite is a self-serve solution optimized for in-article advertising. In-article placements are placed at the core of readers' attention and offer optimum real … clean feathers with beak

VGLL4 promotes osteoblast differentiation by antagonizing TEADs ...

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